Endocrine Abstracts

We identified 65 patients from the departmental endocrine database who had received testosterone (T) therapy. 62 records were reviewed and 7 patients excluded as they received T <6 months. We undertook a retrospective audit examining the routine monitoring of these patients. These 55 patients included; 21 patients with primary hypogonadism (PH) and 34 patients with secondary hypogonadism (SH); mean age (range) 52 (28–75) and 59 (35–91) yrs respectively. 46 (84%) ...

Background: Obesity and subsequent insulin resistance is becoming more frequent among type 1 diabetes (T1DM) patients, leading to ‘double diabetes’ and potentially increasing vascular risk. Studies in double diabetes remain limited and this population is not fully characterised.Aims: To investigate the prevalence of overweight and obese T1DM patients and analyse the effects of increasing weight on cardiovascula...

Background: Obesity and subsequent insulin resistance is becoming more frequent among type 1 diabetes (T1DM) patients, leading to ‘double diabetes’ and potentially increasing vascular risk. Studies in double diabetes remain limited and this population is not fully characterised.Aims: To investigate the prevalence of overweight and obese T1DM patients and analyse the effects of increasing weight on cardiovascula...

We describe the case of a 32-year-old lady Polish lady, who presented to the surgical team at Leeds Teaching Hospitals NHS Trust in July 2012 with abdominal pain and vomiting. The previous year she had undergone a private ‘banded bypass’ operation in Poland resulting in 60 kg weight loss. On admission she was diagnosed with a slipped gastric band, to be confirmed by laparoscopy. Surprisingly the ‘band’ was in fact a length of surgical drain sutured to the m...

Differentiated thyroid cancer (DTC) is common in female patients of reproductive age and generally has a good prognosis and so many patients may become pregnant following treatment. Progression of DTC during pregnancy has been reported and may relate to thyroid stimulation by human chorionic gonadotropin (hCG). Until recently suppression of thyrotropin (TSH) by supraphysiological doses of levothyroxine was indicated for all patients following thyroidectomy and radioiodine abla...

We present a 20-year-old lady who was known to have MEN-1 and had previously been treated for hyperparathyroidism at a different hospital in 2003 with excision of right upper and lower and left lower parathyroid glands and left thyroid lobectomy, resulting in normalisation of adjusted calcium (adjCa) levels.She presented to our department with persistently elevated adjusted calcium levels (adjCa 2.69 mmol/l) along with raised parathyroid hormone (PTH 16 ...

A 24-year-old Asian lady with no past medical history was admitted under the surgical team with right sided abdominal pain, nausea and vomiting, postural dizziness and weight loss. She was give trimethoprim for a possible urinary tract infection along with paracetamol, tramadol and diclofenac. Blood tests on admission demonstrated normal renal, liver and thyroid function, a normal C-reactive protein and full blood count and a low sodium of 131 mmol/l. An abdominal ultrasound w...

There is limited evidence for the role of screening for Cushing’s syndrome (CS). Patients referred to the specialist medical weight management service at Musgrove Park Hospital have routinely been screened for CS with either an overnight dexamethasone suppression test (ODST) or two 24hour urinary free cortisol (UFC) if evidence of dysglycaemia. We retrospectively analysed the results of all patients referred to the service between 2013–2016. 794 patients were seen as...